KMID : 0363220100480111024
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Korean Journal of Dermatology 2010 Volume.48 No. 11 p.1024 ~ p.1026
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Systemic Lupus Erythematosus That Developed in a Child with Chronic Idiopathic Thrombocytopenic Purpura
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Kim Young-Sik
Shin Dong-Hoon Choi Jong-Soo Kim Ki-Hong
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Abstract
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Idiopathic thrombocytopenic purpura (ITP) is a common bleeding disorder in children and it is caused by autoantibodies against platelet surface antigens. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect any part of the body and so result in diverse clinical and laboratory manifestations, including thrombocytopenia. It is known that only 10¡15% of all SLE cases are diagnosed during childhood. Thrombocytopenia may be the sole manifestation early in the course of SLE, whereas SLE can subsequently develop in 1¡ 5% of ITP patients. We report here on an interesting case of SLE that developed in an eleven year-old girl with chronic and refractory ITP and who underwent splenectomy.
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KEYWORD
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Childhood, Idiopathic thrombocytopenic purpura, Systemic Lupus erythematosus
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